The Beal Lab wishes a farewell to undergrads Anthony and Isaac who have completed their Bachelors. Anthony is pursuing a Masters in Computer Science at Carnegie Mellon and Isaac is pursuing a PhD in Chemistry at UCLA. We also wish farewell to Dr. Sukanya who has completed her post-doc with us and begun a post-doc at UC Irvine. We will miss them but are excited to see what they’ll do next!
Christine and Charles presented a third year seminar talk to the first and second year graduate students in the Chemistry Department. Each shared about ADAR RNA editing and the progress they have made on their individual projects. Congratulations to Charles and Christine!
Charles: Enhanced ADAR-based Site-Directed RNA Editing using a guide strand bearing a Uracil Analog with a Modified Sugar
Christine: Screening Modified Oligonucleotide Libraries to identify Motifs that enable Site-Directed RNA Editing with ADAR
Pictured are current members of the Beal and Fisher lab as well as alumni (Melissa Matthews and Agya Karki)!
Prince was awarded the R.B Miller Research, Service, and Mentorship Award! Congratulations to him on this well deserved award!
Natalie delivered a fantastic third year seminar! Congratulations Natalie!
Congratulations to those involved in publishing two chapters in Methods of Enzymology detailing our work on ADAR crystallography and high-throughput guide RNA screening! Check them out here:
Crystallography chapter by Campbell, K et al.: DOI: 10.1016/bs.mie.2024.11.023
EMERGe chapter by Salvador, P et al.: DOI: 10.1016/bs.mie.2024.11.030
We are so excited that two first years, Olivia and Paul, have joined our lab!
Manjunath, A.; Cheng, J.; Campbell, K.B.; Jacobsen, C.S.; Mendoza, H.G.; Bierbaum, L.; Jauregui-Matos, V.; Doherty, E.E.; Fisher, A.J.; Beal, P.A. Nucleoside Analogs in ADAR Guide Strands Enable Editing at 5′-GA Sites. Biomolecules 2024, 14, 1229. DOI: 10.3390/biom14101229
Aash and coworkers discuss enabling editing using nucleobase modifications at challenging-to-edit sites in vitro and in mamallian cells! Congratulations to all that were involved with this project!
Congratulations to Victorio, Olivia and Megan for winning awards at our Chemistry Department Award Ceremony last friday! Victorio (5th year graduate student) was awarded the David and Ruth Volman Graduate Fellowship. We are so very proud of you and are excited for what you bring back after your internship!
Olivia (undergraduate student) was awarded the Larock Outstanding Senior Award and Department Citation for Outstanding Graduating Students, and Megan (undergraduate student) was warded the Department Citation for Outstanding Graduating Students. We have all had the pleasure of watching both of you grow as scientists during your time here in the Beal lab! We will see you in the fall during lab rotations and we are excited to witness what is sure to be a very bright future for you both!
