Recent Publications

Onizuka, K.; Hazemi, M. E.; Thomas, J. M.; Monteleone, L. R.; Yamada, K.; Imoto, S.; Beal, P. A.; Nagatsugi, F., Synthesis of native-like crosslinked duplex RNA and study of its properties. Bioorganic & Medicinal Chemistry 2017, 25 (7), 2191-2199
DOI:10.1016/j.bmc.2017.02.034

Hu, T.; Suter, S. R.; Mumbleau, M. M.; Beal, P. A., TLR8 activation and inhibition by guanosine analogs in RNA: Importance of functional groups and chain length. Bioorganic & Medicinal Chemistry 2017.
DOI:10.1016/j.bmc.2017.11.020

Suter, S. R.; Ball-Jones, A.; Mumbleau, M. M.; Valenzuela, R.; Ibarra-Soza, J.; Owens, H.; Fisher, A. J.; Beal, P. A., “Controlling miRNA-like off-target effects of an siRNA with nucleobase modifications.” Organic & Biomolecular Chemistry 2017.
DOI:10.1039/C7OB02654D

Mizrahi, R.A.; Shin, Dongwon; Sinkeldam, R.W.; Phelps, K.J.; Fin, A.; Tantillo, D.J.; Tor, Y.; Beal, P.A.
“A Fluorescent Adenosine Analogue as a Substrate for an A-to-I Editing Enzyme” Angew.
Chem. Int. Ed.
, 2015, 54(30), 8713-8716. DOI:10.1002/anie.201502070

Wang, Y.; Havel, J.; Beal, P.A. “A Phenotypic Screen for Functional Mutants of Human
Adenosine Deaminase Acting on RNA 1” ACS Chem. Biol.,2015DOI:10.1021/acschembio.5b00711

Kelly J. Phelps, Kiet Tran, Tristan Eifler, Anna L. Ericson, Andrew J. Fisher, and Peter A. Beal*,
“Recognition of duplex RNA by the deaminase domain of the RNA editing enzyme ADAR2”,
Nucl. Acids. Res., 2015,(43)(1), 1123-1132.

Kiet Tran, Michelle R. Arkin, and Peter A. Beal, “Tethering in RNA: An RNA-Binding Fragment
Discovery Tool”, Molecules, 2015,20, 4148-4161.

Kuhn, Claus-D.; Wilusz, Jeremy E.; Zheng, Yuxuan; Beal, PeterA.; Joshua-Tor, Leemor, On-Enzyme Refolding Permits Small RNA and tRNA Surveillance by the CCA-Adding Enzyme, Cell, 2015,
160(4), 644-658. DOI: http://dx.doi.org/10.1016/j.cell.2015.01.005