Manjunath, A.; Cheng, J.; Campbell, K.B.; Jacobsen, C.S.; Mendoza, H.G.; Bierbaum, L.; Jauregui-Matos, V.; Doherty, E.E.; Fisher, A.J.; Beal, P.A. Nucleoside Analogs in ADAR Guide Strands Enable Editing at 5′-GA Sites. Biomolecules 202414, 1229. DOI: 10.3390/biom14101229 

Aash and coworkers discuss enabling editing using nucleobase modifications at challenging-to-edit sites in vitro and in mamallian cells! Congratulations to all that were involved with this project!