Check out new papers from Scott and Tim!
Hu, T.; Suter, S. R.; Mumbleau, M. M.; Beal, P. A., TLR8 activation and inhibition by guanosine analogs in RNA: Importance of functional groups and chain length. Bioorganic & Medicinal Chemistry 2017.
DOI:10.1016/j.bmc.2017.11.020
Suter, S. R.; Ball-Jones, A.; Mumbleau, M. M.; Valenzuela, R.; Ibarra-Soza, J.; Owens, H.; Fisher, A. J.; Beal, P. A., “Controlling miRNA-like off-target effects of an siRNA with nucleobase modifications.” Organic & Biomolecular Chemistry 2017.
DOI:10.1039/C7OB02654D